DUPIXENT is not a steroid. DUPIXENT is a biologic that inhibits IL-4 and IL-13 signaling, two of the key drivers of type 2 inflammation contributing to many conditions, including asthma, atopic dermatitis, chronic obstructive pulmonary disease, chronic rhinosinusitis with nasal polyposis, eosinophilic esophagitis, and prurigo nodularis. The mechanism of dupilumab action has not been definitively established.1-8